Luying Chen
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Long-term impact of antibiotic exposure duration on recurrence and microbial resistance in moderate-to-severe acne: a real-world retrospective analysis
Abstract Background: Systemic antibiotics for moderate-to-severe acne are commonly prescribed, but the optimal duration remains unclear. Prolonged use may increase recurrence rates and antibiotic resistance. This study evaluated the long-term effects of antibiotic duration on acne recurrence and microbial resistance. Methods: This study included a single-center retrospective cohort of 240 patients (12–40 years) with moderate-to-severe acne treated with doxycycline or minocycline (2020–2023).
Cavitary nodule caused by Emergomyces orientalis in a diabetic patient: a case report
Abstract Emergomyces orientalis is a rare thermally dimorphic fungus belonging to the family Ajellomycetaceae. It exists in the environment as a mold producing conidia, which are inhaled and transform into yeast-like cells at body temperature to cause disseminated infections. While primarily associated with immunocompromised individuals, especially those with HIV.
Identifying Bioactive Conformations of Flexible Polyunsaturated Fatty Acids for Ligand-Based Drug Design
Luying Chen Corresponding author School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, Guangdong 510515, China Laboratory of Organic and Medicinal Chemistry, Graduate School of Pharmaceutical Sciences, The University of Tokyo, 7–3–1 Hongo, Bunkyo-ku, Tokyo 113–0033, Japan Mian Wu Laboratory of Organic and Medicinal Chemistry, Graduate School of Pharmaceutical Sciences, The University of Tokyo, 7–3–1 Hongo, Bunkyo-ku, Tokyo 113–0033, Japan Tomohiko Ohwada...
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