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Niraparib Maintenance Treatment Improves Time Without Symptoms or Toxicity (TWiST) Versus Routine Surveillance in Recurrent Ovarian Cancer: A TWiST Analysis of the ENGOT-OV16/NOVA Trial | Journal of Clinical Oncology

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By Ursula Matulonis, Paul H. Bessette, Lydia Walder, Trine J. Nøttrup
| ascopubs.org
Ovarian cancer (OC) was diagnosed in 240,000 women worldwide in 2012.1 Most women are diagnosed with advanced cancer and prognosis is poor, which is reflected by OC being one of the most deadly forms of women’s cancer, with a 5-year survival rate of 47.4% and approximately 151,917 deaths in 2012.1,2 The standard of care for first-line treatment is platinum- and taxane-based chemotherapy, which results in high initial response rates; however, relapse rates for women who are diagnosed with...
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