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Regulation of coronavirus nsp15 cleavage specificity by RNA structure
PLOS ONE, Aug 2023 SARS-CoV-2, the etiologic agent of the COVID-19 pandemic, has had an enduring impact on global public health. However, SARS-CoV-2 is only one of multiple pathogenic human coronaviruses (CoVs) to have emerged since the turn of the century. CoVs encode for several nonstructural proteins (nsps) that are essential for viral replication and pathogenesis.
Regulation of coronavirus nsp15 cleavage specificity by RNA structure
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