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M. L. Barclay on Muck Rack

M. L. Barclay

As seen in: Color Research & Application
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Articles

Randomised clinical trial: efficacy, safety and dosage of adjunctive allopurinol in azathioprine/mercaptopurine nonresponders (AAA Study)

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By S. J. Brown, M. L. Barclay, A. S. Chung, J. c. McKenzie, J. C. Reynolds, P. R. Gibson, M. P. Sparrow, A. B. Friedman, P. Bampton, F. A. Macrae, S. B. Hanauer
| Color Research & Application Verified
Thiopurine hypermethylation towards 6-methylmercaptopurine (6MMP) instead of 6-thioguanine nucleotides (6TGN) is associated with inefficacy in patients with IBD. Allopurinol reverses such hypermethylation. To prospectively determine efficacy of allopurinol-thiopurine combination and to compare 2 doses of allopurinol.
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Randomised clinical trial: efficacy, safety and dosage of adjunctive allopurinol in azathioprine/mercaptopurine nonresponders (AAA Study)

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By A. B. Friedman, S. J. Brown, P. Bampton, M. L. Barclay
| Color Research & Application Verified
Thiopurine hypermethylation towards 6‐methylmercaptopurine (6MMP) instead of 6‐thioguanine nucleotides (6TGN) is associated with inefficacy in patients with IBD. Allopurinol reverses such hypermethylation. To prospectively determine efficacy of allopurinol‐thiopurine combination and to compare 2 doses of allopurinol.
Open in Who Shared Issue with article?

Editorial: vedolizumab as a treatment and cause of extra-intestinal manifestations of inflammatory bowel disease

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By M. L. Barclay, L. K. Stamp
| Color Research & Application Verified
Previous article in issue: Editorial: getting bullish about portal hypertension—chronic treatment with oral taurine? Author's reply Previous article in issue: Editorial: getting bullish about portal hypertension—chronic treatment with oral taurine?
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