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Macoto Fujimoto

As seen in: Nature
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Articles

Advancing PET through direct imaging of three-photon decay using pure positron emitters

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By Riku Sato, Peter Caradonna, Laura Stephenson, Julien Bordes, James Brown, Daniel Watts, Kenji Shimazoe, Macoto Fujimoto, Moh Hamdan, Mizuki Uenomachi, Archie Montgomery
| Nature Verified
Abstract Positronium is abundantly formed inside the human body during positron emission tomography (PET). Its properties, such as lifetime and three-photon decay rate, are highly sensitive to the microenvironment, particularly oxygen partial pressure and the size of free voids. Thus, positronium is a promising biomarker for an imaging modality complementary to conventional PET imaging. Here we achieved positronium ratio imaging through the direct localization of three-photon annihilation events.
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