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Maddala Madhavi on Muck Rack

Maddala Madhavi

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Articles

Generative AI-Driven Discovery and Experimental Validation of a Novel EGFR Inhibitor for the Treatment of Pancreatic Cancer

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By Anuraj Nayarisseri, Vaishnavi Jadhav, Rashmi Sharma, Srinivas Bandaru, Hafiz Farooq Ahmad, Keun Woo Lee, Marcus T. Scotti, Luciana Scotti, Jyothi Kaparapu, Sajal Suhane, Yug Shree, Dhruvi Jungi, Akansha Sankhala, Radhika Swami, Umesh Panwar, Murali Aarthy, Maddala Madhavi, Pranoti Belapurkar
| Nature Verified
Abstract Pancreatic cancer remains a highly lethal malignancy with limited targeted therapeutic options, necessitating the development of effective EGFR-directed inhibitors. In this study, an integrated generative artificial intelligence (AI)-driven computational–experimental workflow was developed to identify a novel EGFR inhibitor, using a cannabigerol-derived scaffold as the initial seed.
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