Madeline O'Connor

1 INTRODUCTION Wound care is a critical aspect of healthcare, and advancements in therapeutic modalities continually seek to enhance the healing process. The transforming powder dressing (TPD), Altrazeal®, is a biologically inert polymer composed of nanoparticles (Figure 1). It was engineered as a dressing for surgical wounds, traumatic wounds, chronic wounds and burns. It is simple and painless to apply, as the powder is sprinkled over a moistened wound.

1 INTRODUCTION Staphylococcus aureus (S. aureus) is a well-known human pathogen and a major cause of morbidity and mortality worldwide. S. aureus infections can occur in every organ system of the human body. It has a predilection for causing chronic and severe disease in immunocompromised patients with comorbidities.1-3 In patients with diabetes, S. aureus is one of the most commonly detected bacteria in skin and soft tissue infections (SSTIs).4-10 Both S.