Madeline P. Matia on Muck Rack

Madeline P. Matia

As seen in: Nature
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Articles

Characterizing and controlling CRISPR repair outcomes in nondividing human cells - Nature Communications

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By Gokul N Ramadoss, Manasi Kumar, Jennifer Hamilton, Rohit Sharma, Alvin Ha, Christof Fellmann, Philip H. Dierks, Barbara Perez, Serena Lu, Brian Shy, Britt Adamson, Niren Murthy, Jennifer Doudna, Martin Kampmann, Julianne Jin, Madeline P. Matia
| Nature
Abstract Genome editing is poised to revolutionize treatment of genetic diseases, but poor understanding and control of DNA repair outcomes hinders its therapeutic potential. DNA repair is especially understudied in nondividing cells like neurons, limiting the efficiency and precision of genome editing in many clinically relevant tissues.
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