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Madhulika Tripathi on Muck Rack

Madhulika Tripathi

As seen in: BioRxiv
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Articles

Estrogen receptor-related receptor (Esrra) induces ribosomal protein Rplp1-mediated adaptive hepatic translation during prolonged starvation

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By Madhulika Tripathi, Karine Gauthier, Reddemma Sandireddy, Jin Zhou
| BioRxiv
Abstract Protein translation is an energy-intensive ribosome-driven process that is reduced during nutrient scarcity to conserve cellular resources. During prolonged starvation, cells selectively translate specific proteins to enhance their survival (adaptive translation); however, this process is poorly understood. Accordingly, we analyzed protein translation and mRNA transcription by multiple methods in vitro and in vivo to investigate adaptive hepatic translation during starvation.
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