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Madsen JL on Muck Rack

Madsen JL

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Dorothy Hodgkin lecture 2023: The enteroendocrine system-Sensors in your guts

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By Frank Reimann, Drucker DJ, Lovshin JA, Madsen JL
| Wiley Online Library Verified
Glucagon-like peptide-1 receptor (GLP1R-) based therapies are now established for the treatment of type2 diabetes and, at higher doses, for the treatment of obesity, with emerging drugs combining GLP1R activity with action at other gut hormone receptors. Research has identified a range of receptors expressed by enteroendocrine cells, the intestinal source of gut peptides including GLP-1, which might be targeted pharmacologically to recruit endogenous hormone reserves.
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