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Mahdiye Ijavi on Muck Rack

Mahdiye Ijavi

As seen in: Nature, Royal Society of Chemistry, BioRxiv
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Articles

A solid beta-sheet structure is formed at the surface of FUS droplets during aging - Nature Chemical Biology

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By Leonidas Emmanouilidis, Ettore Bartalucci, Mahdiye Ijavi, Maria Perez, María Pérez Verified, Pavel Afanasyev, Daniel Boehringer, Sapun H Parekh, Mischa Bonn, Thomas Wiegand
| Nature Verified
Abstract Phase transitions are important to understand cell dynamics, and the maturation of liquid droplets is relevant to neurodegenerative disorders. We combined NMR and Raman spectroscopies with microscopy to follow, over a period of days to months, droplet maturation of the protein fused in sarcoma (FUS). Our study reveals that the surface of the droplets plays a critical role in this process, while RNA binding prevents it.
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A solid beta-sheet structure is formed at the surface of FUS liquid droplets during aging

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By Leonidas Emmanouilidis, Ettore Bartalucci, Mahdiye Ijavi, Yelena Kan
| BioRxiv
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Surface tensiometry of phase separated protein and polymer droplets by the sessile drop method

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By Robert W. Style, Leonidas Emmanouilidis, Mahdiye Ijavi
| Royal Society of Chemistry Verified
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