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Maher Y. Abdalla on Muck Rack

Maher Y. Abdalla

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Heme Oxygenase-1 Inhibition Modulates Autophagy and Augments Arsenic Trioxide Cytotoxicity in Pancreatic Cancer Cells

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By Iman Ahmad, Alicia J. Dafferner, Ramia J. Salloom, Maher Y. Abdalla
| MDPI
1. Introduction Pancreatic ductal adenocarcinoma (PDAC) is an aggressive cancer with a high mortality rate [1]. According to the American Cancer Society, PDAC is the third leading cause of cancer death in men and women combined (about 3% of all cancers in the USA) with an estimated 50,550 people that will die of PDAC in 2023 [2]. One of the major problems in PDAC treatment is drug resistance, thus making new drug strategies ineffective in clinical trials [3].
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