“Dottoré, I don't want to take the medicine. Shouldn’t I be free to decide that for myself?” This question holds everything I resent the most about my work. At this point, I know I have to look the patient in the eye, and without flinching, answer: “No.” In 99% of the cases, the patient will reply: “I’m well enough — I’m not taking it.” And I will have to double down, firmly: “No, you’re not well, and you need to follow the treatment.” “And why’s that?” And here comes the kicker.