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Malay Ranjan Biswal on Muck Rack

Malay Ranjan Biswal

As seen in: BioRxiv
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Articles

Comparative Analysis of Lipid Nanoparticles in Pfizer-BioNTech and Moderna COVID-19 Vaccines: Insights from Molecular Dynamics Simulations

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By Malay Ranjan Biswal, Sudip Roy Verified, Jayant K. Singh, Prescience Insilico
| BioRxiv
Abstract COVID-19 vaccines, such as Pfizer-BioNTech's BNT162b and Moderna's mRNA-1273, have demonstrated robust efficacy. However, direct comparisons of their delivery vehicles remain limited. Notably, BNT162b requires storage at -80°C, while mRNA-1273 is stored at -20°C. This discrepancy in storage temperatures may be influenced by differences in the structure and stability of the lipid nanoparticles (LNPs) used in these vaccines.
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In Silico Engineering of Stable siRNA Lipid Nanoparticles: Exploring the Impact of Ionizable Lipid Concentrations for Enhanced Formulation Stability

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By Sudip Roy Verified, Jayant K. Singh, Malay Ranjan Biswal, Prescience Insilico
| BioRxiv
Abstract Lipid nanoparticles (LNPs) are crucial in advancing the delivery of RNA-based therapeutics within the domain of gene therapy.
Open in Who Shared Issue with article?
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