Malco Rossi

Malco Rossi and Christopher D. Stephen contributed equally to this study. Relevant conflicts of interest/financial disclosures: J.D., J.L.P., C.-Y.R.L., W.-W.L., H.M., O.G.P.B., and A.K.S. report no conflict of interest. M.R. has served on an advisory board for Biogen and has received honoraria for talks from the International Parkinson and Movement Disorder Society and Biogen.

Different variants in the GBA1 gene, encoding the enzyme glucocerebrosidase, either cause a monogenic form of Parkinson's disease (PD, also referred to as PARK-GBA1 by the International Parkinson and Movement Disorder Society Task Force on Genetic Nomenclature in Movement Disorders1) with reduced penetrance or act as genetic risk factors for developing PD or dementia with Lewy bodies (DLB).2-6 Biallelic pathogenic variants cause Gaucher's disease (GD), an autosomal recessive lysosomal storage...

An 80-year-old woman presented to the emergency department with vertigo, right hand incoordination, and postural instability 5 months after rituximab treatment for chronic lymphocytic leukemia. Physical examination revealed dysarthria, horizontal nystagmus, gait ataxia, and right upper and lower limb dysmetria.