malcolm mcleod
Asia–Pacific (APAC)
Articles by malcolm mcleod
Chromatography Tracks Drugs in Australian Wastewater
News|Articles|October 19, 2026 Author(s)Richard Bade , Malcolm McLeod , John Chasse Richard Bade and Malcolm McLeod explain to LCGC International how chromatography detects drug trends in wastewater. Drug and alcohol use is a major problem in Australia, both in terms of cost to society and impact on health. A recent national survey found that nearly half of Australians aged 14 and up have tried an illegal drug at some point in their lives.
LC–MS/MS Tracks Drugs in Australian Wastewater
News|Articles|October 19, 2026 (Updated: October 19, 2026) Author(s)Richard Bade , Malcolm McLeod , John Chasse Richard Bade and Malcolm McLeod explain to LCGC International how liquid chromatography-tandem mass spectrometry (LC-MS/MS) detects drug trends in wastewater. Drug and alcohol use is a major problem in Australia, both in terms of cost to society and impact on health.
The Possessed Machines (summary) — LessWrong
The Possessed Machines is one of the most important AI microsites. It was published anonymously by an ex- lab employee, and does not seem to have spread very far, likely at least partly due to this anonymity (e.g. there is no LessWrong discussion at the time I'm posting this). This post is my attempt to fix that.
Identification of the Novel Synthetic Opioid N‐Pyrrolidino Isotonitazene at an Australian Drug Checking Service
1 Introduction 2-Benzylbenzimidazole opioids and related derivatives, also known as ‘nitazenes’, present a growing threat to public health. Emerging in the recreational drug market in Europe in 2019 [1], the nitazene group of drugs is a recent addition to the novel synthetic opioid class characterised by variable structures and differing potencies that in many cases exceed that of fentanyl [2-6].
A Disciplined Way to Avoid Wireheading — LessWrong
This is a crosspost of a post from my blog, Metal Ivy. The original is here: A Disciplined Way To Avoid Wireheading. The term wireheading comes from the observation that if you put a wire in someone’s brain such that it is near their brain’s pleasure (or craving) center, and give them a lever that when pressed activates the current through the wire, they will repeat that action forever, to the point of dying from starvation. Conditional on them trying it once, of course.
Molecular basis of inhibition of the amino acid transporter B0AT1 (SLC6A19) - Nature Communications
Abstract The epithelial neutral amino acid transporter B0AT1 (SLC6A19) is the major transporter for the absorption of neutral amino acids in the intestine and their reabsorption in the kidney. Mouse models have demonstrated that lack of B0AT1 can normalize elevated plasma amino acids in rare disorders of amino acid metabolism such as phenylketonuria and urea-cycle disorders, implying a pharmacological approach for their treatment.
Show More
loading
Actions
Is this you?
As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.Get in touch with malcolm
Contact malcolm, search articles and posts on X, monitor coverage, and track replies from one place.
Learn more about Muck Rack