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Malindrie Dharmaratne on Muck Rack

Malindrie Dharmaratne

As seen in: BioRxiv
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Articles

Spatial analysis of Hofbauer cell transcriptome, distribution and morphology in placentas exposed to Plasmodium falciparum

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By Rebecca Harding, Malindrie Dharmaratne, Yunshun Chen, Ricardo Ataide
| BioRxiv
Abstract Placental infection remains a significant health burden for mothers and their babies in low-income countries, especially in sub-Saharan Africa, where malaria transmission is intense. An increase in inflammatory biomarkers and poor vascularisation are characteristics of placentas infected with malaria. Hofbauer cells (HBCs) - placental villous macrophages of fetal origin - are one of the most abundant immune cells in the placenta.
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scShapes: A statistical framework for identifying distribution shapes in single-cell RNA-sequencing data

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By Malindrie Dharmaratne, Ameya S Kulkarni, Atefeh Taherian Fard, Jessica C. Mar
| BioRxiv
Abstract Background: Single cell RNA sequencing (scRNA-seq) methods have been advantageous for quantifying cell-to-cell variation by profiling the transcriptomes of individual cells. For scRNA-seq data, variability in gene expression reflects the degree of variation in gene expression from one cell to another.
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Abstract 4426: Redox regulation of tumor cell heterogeneity in the PyMT mammary tumor model revealed by single cell RNA sequencing

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By Ameya S Kulkarni, Atefeh Taherian Fard, Zuen Ren, Malindrie Dharmaratne
| cancerres.aacrjournals.org
Clinical Research (Excluding Clinical Trials) Zuen Ren, Malindrie Dharmaratne, Ameya Kulkarni, Atefeh Taherian Fard, Jessica Mar, Phillip M. Galbo, Yang Liu, Deyou Zheng, Huizhi Liang, Outhiriaradjou Benard, Kimita Suyama, Michael B. Prystowsky, Larry Norton and Rachel B.
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