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Man Ying on Muck Rack

Man Ying

As seen in: AIChE Journal, Biomed Central (BMC)
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Articles

DAP12 deletion reduces neuronal SLIT2 and demyelination and enhances brain resilience in female tauopathy mice - Molecular Neurodegeneration

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By Man Ying
| link.springer.com
Abstract Pathogenic tau accumulation drives neurodegeneration in Alzheimer’s disease (AD). Enhancing the aging brain’s resilience to tau pathology would lead to novel therapeutic strategies. DAP12 (DNAX-activation protein 12), highly and selectively expressed by microglia, plays a crucial role in microglial immune responses. Previous studies have shown that tauopathy mice lacking DAP12 exhibit higher tau pathology but are protected from tau pathology-induced cognitive deficits.
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By Yiwen Jiang, Lingxi Jiang, Zhongwei Yang, Xiaolin Liu, Man Ying, He Huang, Yiren Xu, Hang Zhou, Jincui Huang, Xuejun Gu, Weichang Zhou, Ying Huang
| AIChE Journal Verified
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By Yiwen Jiang, Lingxi Jiang, Zhongwei Yang, Xiaolin Liu, Yaoyao Wang, Man Ying, He Huang, Yiren Xu, Hang Zhou, Xuejun Gu, Weichang Zhou, Ying Huang, Jincui Huang
| AIChE Journal Verified
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