Manas Geeta Arun

Abstract The rate of adaptation is equal to the additive genetic variance for relative fitness VA in the population. Estimating VA typically involves measuring fitness proxies on a large number of individuals from a known pedigree. Such data are hard to collect and the results are often sensitive to the definition of fitness used.

Abstract Sexually antagonistic (SA) selection on a trait with a shared genetic basis between the sexes is thought to lead to Intralocus Sexual Conflict (IaSC). A common way of measuring IaSC involves characterising the joint distribution of breeding values of male and female fitness using the intersexual additive genetic correlation for fitness (rmf,W).

Abstract When selection favours different levels of expression for a shared trait in males and females, the population is said to be in Intralocus Sexual Conflict (IaSC). In a landmark study, Connallon and Clark (2010) showed that modifiers (alleles at a different locus that alter the expression of the trait under IaSC in a sex-specific manner), effectively resolve IaSC.