After a disappointing update on detalimogene voraplasmid in May, EnGene will cut down its workforce by half and let several executives go to focus attention on a H2 2026 FDA filing. (Shutterstock) enGene Therapeutics is cutting its workforce in half and discontinuing several cohorts of a Phase II study to preserve cash ahead of a planned US Food and Drug Administration filing for detalimogene voraplasmid in non-muscle invasive bladder cancer (NMIBC).