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Articles by Manikandan Ekambaram
Mapping the oral microbiome in children with oral diseases using next-generation sequencing: a systematic review
Abstract Background The oral microbiome is integral to paediatric oral health and disease. Next-generation DNA sequencing (NGS) technology enables culture-independent profiling of microbial communities, yet findings remain inconsistent due to methodological and population heterogeneity. Objective This review synthesised NGS-based evidence comparing the oral microbiome of children/adolescents with oral diseases and healthy controls. Design The protocol was registered in PROSPERO (CRD42025618407).
Reimagining workforces: How GCCs and GSIs are becoming global talent engines
Global Capability Centers (GCCs) and Global System Integrators (GSIs) are no longer cost-saving support units. They are becoming engines of talent and innovation—and India sits at the heart of this transformation. The shift is disruptive, positioning India as the epicentre of enterprise innovation, leadership development, and technological breakthroughs. The question is no longer whether India can lead, but how decisively it will shape the global technology economy.
Sustainability of Improvement in Oral‐Health‐Related Quality of Life Following Dental Treatment Under General Anaesthetic: The Role of Family Functioning
Why this paper is important to paediatric dentists ○ It shows that the improvement in oral-health-related quality of life (OHRQoL) following treatment under GA for ECC persists to at least 12 months post-treatment. ○ Family functioning does not appear to play an important role in the degree of that improvement. 1 Introduction Early childhood caries (ECC) is a cumulative condition that remains highly prevalent among young children [1].
In Vitro Models Used in Cariology Mineralisation Research-A Review of the Literature
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Prevention of Demineralization during Multi‐ bracketed Fixed Orthodontic Treatment: An Overview of Systematic Reviews
SYSTEMATIC REVIEW Divesh Sardana, orcid.org/0000-0002-6486-5893 Research Postgraduate Student, Paediatric Dentistry and Orthodontics, Faculty of Dentistry, The University of Hong Kong, Hong Kong S.A.R, Hong Kong Search for more papers by this author Sheetal Manchanda, Research Postgraduate Student, Paediatric Dentistry and Orthodontics, Faculty of Dentistry, The University of Hong Kong, Hong Kong S.A.R, Hong Kong Search for more papers by this author Manikandan Ekambaram,...
Synbiotics in caries prevention: A scoping review
Loading metrics Open Access Peer-reviewed Research Article Mohammed Nadeem Bijle , Manikandan Ekambaram , Edward C. M. Lo , Cynthia Kar Yung Yiu Mohammed Nadeem Bijle, Manikandan Ekambaram, Edward C. M. Lo, Cynthia Kar Yung Yiu Published: August 12, 2020 https://doi.org/10.1371/journal.pone.0237547 Figures Abstract The scoping review aimed to examine the evidence on the role of synbiotics in caries prevention. PubMed, SCOPUS, and Web of Science databases search were performed.
Quality of life changes in children following emergency dental extractions under general anaesthesia
To assess the changes in the oral health-related quality of life (OHRQoL) of 221 preschool children who presented to the emergency department with the consequences of untreated dental caries requiring dental extractions under general anaesthesia (DEGA). Two hundred and twenty-one healthy preschool children, who required emergency DEGA, were recruited over a period of 12 months.
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