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Manish Raj Kharel

As seen in: Wiley Online Library
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Articles

Use of lecanemab for the treatment of Alzheimer's disease: A systematic review

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By Fahad Hossain, Manish Raj Kharel, Ashma Ul Husna
| Wiley Online Library Verified
1 INTRODUCTION Alzheimer's disease (AD), also known as dementia, is a serious neurological condition marked by behavioral abnormalities, memory loss, and progressive cognitive deterioration. Although the exact causes of AD are still unknown, it is commonly accepted that the buildup of amyloid beta (Aβ) oligomers plays a significant role in the disease's etiology (Goedert & Spillantini, 2006; Klein et al., 2001).
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A case report of cutaneous tuberculosis

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By Manish Raj Kharel, Fahad Hossain, Manish Kharel MBBS
| Wiley Online Library Verified
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Pituitary apoplexy associated with bacterial meningitis: Diagnostic dilemma

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By Manish Raj Kharel, Fahad Hossain
| Wiley Online Library Verified
1 INTRODUCTION Pituitary apoplexy, a dangerous medical illness with an incidence of 6.2 instances per 100,000 persons, is brought on by an abrupt ischemic infarction or hemorrhage of the pituitary gland.1, 2 It generally affects people around the age of 51.1 years, with 60% of cases being male, and its yearly recurrence rate is 0.17 episodes per 100,000 people.3, 4 Pituitary apoplexy risk varies from 0.6% to 10% in patients with treated pituitary adenomas, but it is 0.6 cases per 100...
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