Manjunath S. Lokolkar

Investigations on the complexation and binding mechanism of bovine serum albumin with Ag-doped TiO2 nanoparticles It is very important to study the interaction between nanoparticle and protein for the better understanding of biological interactions of nanoparticles. In this article, we studied the protein adsorption mode to the surface of the Ag-doped TiO2 nanoparticles (NPs) by taking model protein, Bovine Serum Albumin (BSA).

Pd-Catalysed Synthesis of Oxomalonamides Through Adjacent Triple Carbonylation of Tertiary Amines The monocarbonylation and dicarbonylation reactions are well-established reactions in the carbonylation chemistry. This work reports unusual oxidative adjacent triple carbonylation of tertiary amine towards oxomalonamide synthesis using Pd catalyst.

A simple, cost-effective, and straightforward method for the synthesis of 2,3-disubstituted indole scaffolds has been developed. The present protocol involves copper-mediated tandem hydroamination followed by C–H annulation of unprotected anilines with a wide range of internal alkynes. In the presence of Cu(OAc)2·H2O and trifluoroacetic acid (TFA), the reaction proceeds well to afford a variety of substituted indole derivatives in moderate to good yields.