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Maoyin He on Muck Rack

Maoyin He

As seen in: Frontiers
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Articles

1,8-Cineole improves hepatic fibrosis by inhibiting HIF-1α/BNIP3/PINK1/Parkin-dependent mitophagy signaling and inducing apoptosis in activated hepatic stellate cells

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By Lifeng Qin, Chan He, Jiqiao Zhang, Jiawu Tan, Maoyin He
| Frontiers
Abstract Aim: The HIF-1α/BNIP3/mitophagy signaling pathway might be closely associated with hepatic fibrosis. Although 1,8-cineole (CIN) has been shown to improve fibrosis in several organs, direct evidence for its anti-hepatic fibrotic effects remains lacking. The objective of this study was to confirm the role of mitophagy in hepatic stellate cells (HSCs) and the role of the HIF-1α/BNIP3 signaling pathway in the pathogenesis of hepatic fibrosis.
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