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Maoying Han on Muck Rack

Maoying Han

As seen in: Nature
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Articles

Highly regional generation and heterogeneous differentiation of basal cells in mouse trachea

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By Xiuxiu Liu, Wendong Weng, Zhen He, Kuo Liu, Maoying Han, Wenjuan Pu, Bin Zhou
| Nature Verified
Dear Editor, The trachea connects the lungs to the external environment as part of the respiratory system. Its ventral side is supported by a C-shaped cartilage, while the dorsal side contains smooth muscle. Inside, the pseudostratified epithelium consists mainly of basal cells, secretory cells, and ciliated cells1. Basal cells function as the primary stem cell population, maintaining tissue balance through self-renewal and differentiation2.
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Functional ProTracer identifies patterns of cell proliferation in tissues and underlying regulatory mechanisms - npj Regenerative Medicine

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By Xiuxiu Liu, Maoying Han, Yulong He, Qing-Dong Wang, Jan S. Tchorz
| Nature Verified
Abstract A genetic system, ProTracer, has been recently developed to record cell proliferation in vivo. However, the ProTracer is initiated by an infrequently used recombinase Dre, which limits its broad application for functional studies employing floxed gene alleles.
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Tenascin C+ papillary fibroblasts facilitate neuro-immune interaction in a mouse model of psoriasis - Nature Communications

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By Xiaojie Cai, Maoying Han, Libo Sun, Bin Zhou, Taiyu Zhang
| Nature Verified
Abstract Dermal fibroblasts and cutaneous nerves are important players in skin diseases, while their reciprocal roles during skin inflammation have not been characterized. Here we identify an inflammation-induced subset of papillary fibroblasts that promotes aberrant neurite outgrowth and psoriasiform skin inflammation by secreting the extracellular matrix protein tenascin-C (TNC).
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