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Design, synthesis and evaluation of L-quebrachitol derivatives against α-glycosidase
Design, synthesis and evaluation of L-quebrachitol derivatives against α-glycosidase Maoying Zhang, Xinjie Liang, Pengchen Cai, Qi-Xun Feng, Chen Yongsong, Yu Xiaoxi, Kuo Zhang, Xuefei Bao and Guoliang Chen Abstract Two series of L-quebrachitol derivatives have been designed and synthesized in order to search for novel hypoglycemic agents. The α-glycosidase inhibitory activities of these compounds were evaluated, and their structure-activity relationships (SARs) were discussed.
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