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Branched-chain α-ketoacid dehydrogenase activation reveals divergent sphingolipid and adipokine responses in adipocytes differentiated from visceral adipose-derived mesenchymal stromal cells (ADMSCs)
Abstract Adipose-derived mesenchymal stromal cells (ADMSCs) display heterogeneous metabolic responses that may underlie variable adipocyte phenotype and function. Here, we investigated the effects of BT2, a branched-chain α-ketoacid dehydrogenase (BCKDH) kinase inhibitor, on sphingolipid metabolism, phosphorylation of proteins involved in insulin action, and adipokine secretion using mature adipocytes differentiated from visceral ADMSCs obtained from non-obese and obese men.
Urothelial Urinary Bladder Cancer Is Characterized by Stage-Dependent Aberrations in Metabolism of Bioactive Sphingolipids
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Entrained Flow Plasma Gasification of Sewage Sludge–Proof-of-Concept and Fate of Inorganics
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited.
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