Marcus I Hogan on Muck Rack

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Articles

Experience-dependent reorganization of inhibitory neuron synaptic connectivity

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By Samuel P. Muscinelli, Shuqi Wang, Daniel Fine English, Marcus I Hogan
| biorxiv.org
Abstract Organisms continually tune their perceptual systems to the features they encounter in their environment. We have studied how ongoing experience reorganizes the synaptic connectivity of neurons in the olfactory (piriform) cortex of the mouse. We developed an approach to measure synaptic connectivity in vivo, training a deep convolutional network to reliably identify monosynaptic connections from the spike-time cross-correlograms of 4.4 million single-unit pairs.
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