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Margot Bardou on Muck Rack

Margot Bardou

As seen in: Science Magazine
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Articles

Lymph node microenvironment remodeling unlocks local antibody-mediated B cell depletion

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By Mengchun Wu, Adithya Sarma, Julia Bos, Zacarías García, Margot Bardou, Anne Loap, Lea C. Feldmann, Ophélie Godon, Marion Guérin, Fabrice Lemaître, Lynn E. Macdonald, Pierre Bruhns, Nicolas Serafini, Philippe Bousso, Capucine L. Grandjean
| Science Magazine Verified
Abstract INTRODUCTION RESULTS DISCUSSION MATERIALS AND METHODS Acknowledgments Supplementary Materials REFERENCES Information & Authors Metrics & Citations View Options References Figures Tables Media Share Abstract Lymph nodes (LNs) can act as reservoirs in CD20+ B cell malignancies and autoimmune diseases.
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Anti-PD-1 therapy triggers Tfh cell-dependent IL-4 release to boost CD8 T cell responses in tumor-draining lymph nodes

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By Mathilde Ruggiu, Marion Guérin, Béatrice Corre, Margot Bardou
| rupress.org
Blockade of the PD-1/PD-L1 axis has demonstrated a strong activity during treatment of several cancers, including melanoma (Robert et al., 2015; Weber et al., 2015), non-small-cell lung cancer (Herbst et al., 2016; Reck et al., 2016), and hematologic malignancies such as Hodgkin lymphoma (Armand et al., 2016).
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