Margot M Bartelings

4. Discussion In this study, we systematically described the myocardial alterations in the full spectrum of TGA in uncorrected specimens as well as after surgical correction (Mustard/Senning or ASO). The key finding of our study is that interstitial myocardial fibrosis is already present in young uncorrected TGA hearts in both the systemic RV and subpulmonary LV. More fibrosis was observed in older uncorrected TGA patients.

Original research article Coronary anatomy in Turner syndrome versus patients with isolated bicuspid aortic valves Wilke M C Koenraadt1, Hans-Marc J Siebelink1, Margot M Bartelings2, Martin J Schalij1, Maureen J van der Vlugt3, Annemien E van den Bosch4, Ricardo P J Budde4,5, Jolien W Roos-Hesselink4, Anthonie L Duijnhouwer3, Allard T van den Hoven4, Marco C DeRuiter2, Monique R M Jongbloed1,2 1 Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands 2 Department...

Objective Variations in coronary anatomy, like absent left main stem and left dominant coronary system, have been described in patients with Turner syndrome (TS) and in patients with bicuspid aortic valves (BAV). It is unknown whether coronary variations in TS are related to BAV and to specific BAV subtypes. Aim To compare coronary anatomy in patients with TS with/without BAV versus isolated BAV and to study BAV morphology subtypes in these groups.