Maria Barbi

Hi! I’m Maria — 16, curious, and probably way too interested in things most people find boring. This blog is my space to think out loud. Not as an expert — but as someone who actually cares. I’ll be writing about international relations, civic engagement, and sometimes just trying to make sense of the chaos we live in. I know “politics” can sound like noise or something far away from our daily lives — but it’s not. And I want to prove that here.

Abstract Involved in mitotic condensation, interaction of transcriptional regulatory elements and isolation of structural domains, loop formation has become a paradigm in the deciphering of chromatin architecture and its functional role. Despite the emergence of increasingly powerful genome visualization techniques, the high variability in cell populations and the randomness of conformations still make loop detection a challenge.

Antony Lesage1, Vincent Dahirel2, Jean-Marc Victor1 and Maria Barbi1Email author Epigenetics & Chromatin201912:28 https://doi.org/10.1186/s13072-019-0269-6 ©  The Author(s) 2019 Received: 27 December 2018 Accepted: 6 April 2019 Published: 13 May 2019 Abstract Background Localized functional domains within chromosomes, known as topologically associating domains (TADs), have been recently highlighted.