Maria Camilla Cerlesi on Muck Rack

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Characterisation of the Novel Mixed Mu-NOP Peptide Ligand Dermorphin-N/OFQ (DeNo)

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By Mark Brown, Mark F. Bird, Maria Camilla Cerlesi, Davide Malfacini, Vanessa Vezzi
| PLOS
Opioid receptors are currently classified as Mu (μ), Delta (δ), Kappa (κ) plus the opioid related nociceptin/orphanin FQ (N/OFQ) peptide receptor (NOP). Despite compelling evidence for interactions and benefits of targeting more than one receptor type in producing analgesia, clinical ligands are Mu agonists.
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