English Aim: To report a case of a patient with a brain abscess with a focus of odontogenic origin. Clinical case: A 30-year-old male patient arrives at the Emergency Service of the Interzonal General Hospital “Dr. José Penna” from Bahía Blanca with an intense headache lasting seven days. A brain abscess was diagnosed, so drainage surgery and treatment with antibiotics were performed. The origin was an odontogenic infection, which was treated in the Dentistry Service.