Maria Gil on Muck Rack

Maria Gil

Verified
Spain
As seen in: Financial Food, Un Buen Día en Madrid, Nature, Wiley Online Library, El Español, Frontiers, MDPI, SPORT, Taylor & Francis Online, TechRadar, Antena 3, El Periódico and
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Articles

Structure-based screening and a conformational biosensor identify a GPR183 inverse agonist and an activation switch

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By Louise C Andersson, Michele Roggia, Kittikorn Wangriatisak, Rhiannon Skye Kozel, Sonia Youhanna, Maria Gil , María Gil, Mathias Haag, Volker M Lauschke, Karine Chemin, Holly R. Brittain, Sandro Cosconati, Paweł Kozielewicz
| Nature
Abstract GPR183 is a chemotactic GPCR involved in immune cell migration. Using AI-driven virtual screening and biophysical assays, we identify inverse agonists. From 70 compounds and a subsequent hit expansion, compound 78 emerges as a potent inhibitor of constitutive and agonist-induced Gi signaling as well as β-arrestin2 recruitment. Binding within the receptor core is confirmed by a conformational biosensor, molecular dynamics simulations, and mutagenesis.
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Encrucijadas pedagógicas, simiente y cimiento de saberes en la formación inicial

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By Patricia Mónica Clavijo, Maria Gil , María Gil, Romina Paola Nievas
| Dialnet - Universidad de La Rioja
English The process of teacher training involves facing unexpected situations in the secondary school classroom. These events, which we call pedagogical crossroads, challenge the knowledge acquired in initial training, causing discomfort and forcing practitioners to seek solutions that require original decision-making in the urgency of their practices. Crossroads become pedagogical experiences when they undergo the shutter of reflection.
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Curs de Carretons Elevadors: Conducció i Prevenció de Riscos a Cornellà de LLobregat

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By Maria Gil , María Gil
| Unió de Pagesos
Data: 4, 5, 8, 9 i 11 de juny de 2026 Horari: de 9.30 h a 15.30 h Durada: 30 hores Llocs de realització: Sant Boi de Llobregat (C/ Mossén Cinto Verdaguer, 86) Cornellà de Llobregat (C/ de l’Energia, 114) Descripció: Formació teòrica i pràctica sobre la conducció segura de carretons elevadors i la prevenció de riscos laborals associats a la seva utilització.
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