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Maria Scala on Muck Rack

Maria Scala

Toronto
As seen in: Frontiers, MDPI, Taylor & Francis Online, Literary Mama, International Boat Industry
Writer, Editor, and Food Allergy Mamma. “There is a crack in everything./ That’s how the light gets in.”-Leonard Cohen
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Articles

Full article: New green base for Fmoc removal in solid-phase peptide synthesis: 1,5-diazabicyclo[4.3.0]non-5-ene (DBN), a promising sustainable alternative to piperidine

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By Maria Scala, Giovanni Vivenzio, Michele Manfra, Marina Sala
| Taylor & Francis Online
ABSTRACT Developing greener synthetic methodologies requires replacing hazardous reagents with more sustainable alternatives. In solid-phase peptide synthesis (SPPS), piperidine is the standard base for Fmoc group removal, but its toxicity, environmental concerns, and regulatory restrictions have prompted the search for safer substitutes. This study evaluates various green bases based on their GSK greenness score and chemical–physical properties similar to piperidine.
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Low‐grade epilepsy‐associated tumors: Epilepsy outcome and antiseizure medication discontinuation after lesionectomies as first‐line surgical approach in pediatric population

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By Pia Bernardo, AORN Naples Italy, Maria Scala, Alfonso Rubino
| pericles.pericles-prod.literatumonline.com
Supporting Information Filename Description epd220234-sup-0001-Test_Yourself_Answers.docxWord 2007 document , 15 KB Data S1. epd220234-sup-0002-FigureS1.zipZip archive, 792.3 KB Figure S1. REFERENCES 1, , , , , , et al. The long-term surgical outcomes of low-grade epilepsy-associated neuroepithelial tumors. Epilepsia Open. 2022; 7: 697–709. 2, , , , , , et al. Epilepsy surgery of “low grade epilepsy associated neuroepithelial tumors”: a retrospective nationwide Italian study. Epilepsia.
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Rational Design of Novel Peptidomimetics against Influenza A Virus: Biological and Computational Studies

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By Maria Scala, Magda Marchetti, Fabiana Superti, Mariangela Agamennone
| MDPI
1. Introduction Influenza A virus (IAV) is an extremely infectious pathogen endowed with zoonotic potential and represents one of the leading causes of morbidity and mortality worldwide [1,2]. Over the decades, it has triggered several pandemics, causing major public health problems as well as severe economic losses [3,4]. Flu therapy is based on vaccine prevention and antiviral drug treatment. However, vaccines have several limitations.
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