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Marianne Guilbard

As seen in: Nature, Wiley Online Library
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Articles

Complementary intra- and extracellular AGR2 activities support epithelial ovarian cancer cell aggressiveness

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By Marianne Guilbard, Marc Aubry, Jacques Robert, Valérie Velasco, Romane Florent, Louis-Bastien Weiswald, Coriolan Lebreton, Sabrina Croce, Guillaume Babin, Cédric Chaveroux, Stéphanie Beq, Eric Chevet, Delphine Fessart, Saïd Taouji, Raphael Pineau, Cecile Hartog, Alix Coulon, Frédéric Delom
| Nature Verified
Abstract Anterior Gradient 2 (AGR2) is an endoplasmic reticulum (ER)-resident protein that belongs to the protein disulphide isomerase (PDI) family, and whose expression and secretion are induced by stress. Extracellular (secreted) AGR2 has been proposed as a marker of ER stress–related proteostasis alterations. Cancer cells frequently overexpress intracellular AGR2 (iAGR2) and secrete extracellular AGR2 (eAGR2).
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Endoplasmic reticulum homeostasis-From molecules to organisms: Report on the 14th International Calreticulin Workshop, Saint Malo, France

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By Ketsia Bakambamba, Federico Di Modugno, Marianne Guilbard, Simon Le Goupil
| Wiley Online Library Verified
Federico Di Modugno, Ketsia Bakambamba, Marianne Guilbard, Simon Le Goupil are equally contributed. Abstract The Calreticulin Workshop, initiated in 1994 by Marek Michalak in Banff (Alberta, Canada), was first organized to be an informal scientific meeting attended by researchers working on diverse biological questions related to functions associated with the endoplasmic reticulum (ER)-resident lectin-like chaperone and applied to a wide range of biological systems and models.
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