Marie Angele Cucci

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1. Introduction The incidence of both non-melanoma-skin cancers (NMSCs), and melanoma skin cancers has been increasing over the past years. Globally, in 2020, 1,198,073 new NMSC cases and 63,731 deaths occurred worldwide; of them, 324,635 were new melanoma cases, which caused 57,043 deaths [1]. Recent evidence points out the role of microbiota, the unique combination of micro-organisms residing in a specific environment, in the pathogenesis of several diseases, including skin cancer.