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Articles

Genetics of Brain Fiber Architecture and Intellectual Performance

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By Ming-Chang Chiang, Marina Barysheva, David W. Shattuck, Agatha D. Lee, Sarah K. Madsen
| JNeurosci Verified
The study is the first to analyze genetic and environmental factors that affect brain fiber architecture and its genetic linkage with cognitive function. We assessed white matter integrity voxelwise using diffusion tensor imaging at high magnetic field (4 Tesla), in 92 identical and fraternal twins. White matter integrity, quantified using fractional anisotropy (FA), was used to fit structural equation models (SEM) at each point in the brain, generating three-dimensional maps of heritability.
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