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JCM | Free Full-Text | Quantification of Myocardial Contraction Fraction with Three-Dimensional Automated, Machine-Learning-Based Left-Heart-Chamber Metrics: Diagnostic Utility in Hypertrophic Phenotypes and Normal Ejection Fraction
1. Introduction When conventional endocardial measurements of ejection fraction (EF) are used to assess left ventricular (LV) function, the increases in wall thickness or decreases in diameters might mask the existence of a significant impairment in systolic performance [1,2]. Experimental [3,4] and clinical studies using strain analysis [5] have demonstrated that less fiber shortening is required to achieve a comparable EF in a thick-walled compared to a thin-walled LV.
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