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Subthalamic Activity Is Associated With Proactive Inhibition in Parkinson's Disease Patients
Article Dans Une Revue European Journal of Neuroscience Année : 2025 Subthalamic Activity Is Associated With Proactive Inhibition in Parkinson's Disease Patients Fichier principal Damiani et al. - 2025 - Subthalamic Activity Is Associated With Proactive .pdf (3.26 Mo) Télécharger le fichier hal-05113876 , version 1 (16-06-2025) HAL Id : hal-05113876 , version 1 DOI : 10.1111/ejn.70055 Luna Damiani, Marion Marion Albares, Pauline Laviron, Jean‐eudes Le Douget, Philippe Boulinguez, et al..
Subthalamic Activity Is Associated With Proactive Inhibition in Parkinson's Disease Patients
BG basal ganglia DBS deep brain stimulation dmPFC dorsomedial prefrontal cortex DOPA dopamine medication GAMM generalized additive mixed model ICD impulse-control disorder LFB low-frequency band LFP local field potential LMM linear mixed model PD Parkinson's disease RT reaction time SMA supplementary motor area STN subthalamic nucleus UPDRS Unified Parkinson's Disease Rating Scale 1 Introduction Efficient actions require both the activation of desired behaviours and the inhibition of...
Clonidine modulates the activity of the subthalamic‐supplementary motor loop: evidence from a pharmacological study combining DBS and EEG recordings in Parkinsonian patients - Spay - - Journal of Neurochemistry - Wiley Online Library
Clonidine is an anti‐hypertensive medication which acts as an alpha‐adrenergic receptors agonist. As the noradrenergic system is likely to support cognitive functions including attention and executive control, other clinical uses of clonidine have recently gained popularity for the treatment of neuropsychiatric disorders like attention‐deficit hyperactivity disorder or Tourette syndrome, but the mechanism of action is still unclear.
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