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Maritchka Ryniejska on Muck Rack

Maritchka Ryniejska

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Articles

The prevalence of chronic traumatic encephalopathy in a historical epilepsy post‐mortem collection

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By Maritchka Ryniejska, Hanaa El-Hachami, Alicja Mrzyglod, Joan Liu
| Wiley Online Library Verified
1 INTRODUCTION There is ongoing interest and controversy surrounding the clinical significance of tau protein accumulation in patients with epilepsy. Tau promotes epileptogenesis in diverse animal models [1]; the most compelling evidence comes from studies which demonstrated that reduction of Tau load reduced excitability, seizures and normalised hippocampal networks [2-4]. Focal accumulation of phosphorylated tau (pTau) has been variably reported in epilepsy surgical resections [5, 6].
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