Mark AJ Chaplain on Muck Rack

Mark AJ Chaplain

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Articles

Modelling cancer cell dormancy in mice: statistical distributions predict reactivation times and survival dynamics

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By Nikolaos Sfakianakis, Dimitrios Katsaounis, Mark AJ Chaplain
| biorxiv.org
Abstract In predicting metastatic potential and improving treatment outcomes in cancer research, it is crucial that we understand the dynamics of cancer cell dormancy and reactivation. In this paper we propose, study, and evaluate a cancer growth model that incorporates cell death, dormancy, reactivation, and proliferation in the secondary sites.
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A genuinely hybrid, multiscale 3D cancer invasion and metastasis modelling framework

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By Dimitrios Katsaounis, Thomas Williams, Nicholas Harbour, Mark AJ Chaplain
| biorxiv.org
Abstract We introduce in this paper substantial enhancements to a previously proposed hybrid multiscale cancer invasion modelling framework to better reflect the biological reality and dynamics of cancer. These model updates contribute to a more accurate representation of cancer dynamics, they provide deeper insights and enhance our predictive capabilities.
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