Mark Brook on Muck Rack

Mark Brook

Australia
As seen in: MSN, Daily Mail, MSN Australia, Nature, JAMA Oncology, New Zealand Herald, News24, SBS, The American Journal of Human Genetics, The Lancet and
Entertainment reporter | Opinions are my own.
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Articles

Bindi Irwin on marriage, motherhood and a 'really hard' family question

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By Mark Brook, Katherine Davison 
| New Idea
“Falling in love with you was immediate,” Bindi Irwin told her husband Chandler Powell on their fourth wedding anniversary. “Loving you more every day is utterly effortless. All these years later and every time you smile at me, my heart skips a beat. Here’s to a lifetime of love.” The 27-year-old daughter of the late wildlife warrior Steve Irwin has certainly found her match in the 28-year-old American wakeboard champion.
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Inside John Aiken’s meant to be love story with wife Kelly Swanson-Roe

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By Mark Brook, Briannah Devlin 
| New Idea
Relationship expert John Aiken has made a name for himself as one of the nation’s leading dating gurus on the reality TV social experiment Married At First Sight. After being a fixture on the show for 12 seasons and helping hopeless romantics find their happily ever after, it’s fair to say the 55-year-old knows a thing or two about love.
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A PSA SNP associates with cellular function and clinical outcome in men with prostate cancer - Nature Communications

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By Joan Röhl, Johanna Schleutker, Kenneth Muir, Henrik Grönberg, Nora Pashayan, Demetrius Albanes, Alicja Wolk, Robert MacInnis, Ana Francisca Vega , Børge G Nordestgaard, Hermann Brenner, Marija Gamulin, Frank Claessens, Christel Häggström, Tokhir Dadaev, Mark Brook, Amanda B. Spurdle, Hannu Koistinen, Zsofia Kote-Jarai, Robert Klein, Hans Lilja, Rupert Ecker, Rosalind A. Eeles, Judith Clements, Karina Dalsgaard Sorensen, Ann-Charlotte Rönn
| Nature
Abstract Genetic variation at the 19q13.3 KLK locus is linked with prostate cancer susceptibility in men. The non-synonymous KLK3 single nucleotide polymorphism (SNP), rs17632542 (c.536 T > C; Ile163Thr-substitution in PSA) is associated with reduced prostate cancer risk, however, the functional relevance is unknown. Here, we identify that the SNP variant-induced change in PSA biochemical activity mediates prostate cancer pathogenesis.
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