EpigenomicsAhead of Print Review , , , , , Yuzhuo Wang https://orcid.org/0000-0002-9749-8591 Department of Experimental Therapeutics, BC Cancer Research Centre, 675 West 10th Avenue, Vancouver, BC, V5Z 1L3, Canada Department of Urologic Sciences, The Vancouver Prostate Centre, The University of British Columbia, 2660 Oak St, Vancouver, BC, V6H 3Z6, Canada & Francesco Crea *Author for correspondence: Tel.: +44 1908 654834; E-mail Address: francesco.crea@open.ac.uk...