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Articles by Mark Molnar
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Public Health Decision-Maker Perspective on Joint Clinical Assessments in Central European EU Member States
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Efficient construction of ABC-tricyclic core of schweinfurthins and its application in amide based analog synthesis
Efficient construction of ABC-tricyclic core of schweinfurthins and its application in amide based analog synthesis To accelerate the medicinal chemistry efforts, an efficient and reliable synthesis of amide isosteres of Schweinfurthin G, where the central olefinic linkage between C and D rings has been replaced with amide bond, is described.
Synthesis of Pseudo-Glycoside hybrid steroid dimers NMR and X-ray characterization
Introduction Glycosides comprise an important class of secondary metabolites that are present in a wide diversity of marine and terrestrial organisms [1]. Due their wide distribution and extremely varied biological activities, these compounds have remained in the focus of attention for more than one century. Steroid saponins constitute a heavily populated subfamily of glycosides. A high number of steroids isolated from plants occur as glycosides.
Improving the mechanical properties of vulcanizates containing ground tire rubber: Recipe optimization with the Taguchi method
1 INTRODUCTION Elastomers are cross-linked materials, which are capable of significant reversible deformation at room temperature, which makes them very popular.
One-pot synthesis of 1,3-diazaheterocycles via hydroxylamine hydrochloride activation of anthranilamide/phenylenediamines and DMF derivatives
Many biologically important molecules, including natural products and drugs contain 1,3-diazaheterocyclic compounds such as 4(3H)-quinazolinones and benzimidazoles. [1]. For example, Pegamine, isolated from Peganum harmala, synthetic drugs Nolatrexed and Raltitrexed have been approved as anticancer drug candidates (Fig. 1) [2]. Over the years, synthetic studies have focused on 1,3-diazaheterocyclic compounds due to their distinctive biological activity outcomes.
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