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Articles by Mark Sims
Cardiac ventricular Kir6.1 ATP-sensitive potassium channels: an overlooked effector of cardioprotection
Abstract Introduction: Adenosine triphosphate (ATP)-sensitive potassium (KATP) channels are octameric structures, comprising a pore-forming homotetramer of Kir6.1 or Kir6.2, with 4 accessory sulphonylurea receptor (SUR) subunits. The canonical ventricular KATP channel is the highly ATP-sensitive Kir6.2/SUR2A complex, which is largely inactive under normal physiological conditions.
A Modular Approach to Tuning Emissive N-Quinolyl Through-Space Charge Transfer States Using sp3-Scaffolds
Introduction Click to copy section linkSection link copied! Charge transfer (CT) in organic fluorophores is a fundamental photophysical process that can be either beneficial, e.g., facilitating thermally activated delayed fluorescence (TADF), (1,2) or detrimental, e.g., mediating emission quenching.
A Modular Approach to Tuning Emissive N-Quinolyl Through-Space Charge Transfer States Using sp3-Scaffolds
Introduction Click to copy section linkSection link copied! Charge transfer (CT) in organic fluorophores is a fundamental photophysical process that can be either beneficial, e.g., facilitating thermally activated delayed fluorescence (TADF), (1,2) or detrimental, e.g., mediating emission quenching.
Smoky Mountain Heritage Center brings music to the mountains
There’s nothing that says education and entertainment can’t go hand in hand. For the past 12 years, the Great Smoky Mountain Heritage Center in Townsend has made that synergy an ongoing part of its mission by offering an array of events and offerings that not only reflects the character of the community, but also allows both locals and visitors to enjoy an ongoing array of quality concerts.
Transgender case in Berks County school district heads to court
A federal appeals court hearing is slated to start Thursday on a lawsuit challenging a Berks County School District’s policy for transgender students. It’s one of three cases involving transgender equality which will be heard across the nation this week. The Third Circuit Court of Appeals in Philadelphia will be hearing a case in which a Boyertown Area School District student identified as Joel Doe is challenging a school district policy.
Does Fort Worth ever cross your mind?
Does Fort Worth ever cross your mind? When Fort Worth does cross your mind, I would bet your first thought is of a Longhorn steer. Rightfully so, as Fort Worth was one of the stops on the Chisholm Trail, along which Longhorn cattle were driven north in hopes of capturing higher prices. The city has a rich history in the cattle business. It is home to the Fort Worth Stockyards, which at one time was one of the largest stockyards in the United States.
Seraph Brass to kick off concert series Sept. 20
The Hutchinson Concert Association will kick off its new season with Seraph Brass at 7 p.m. Tuesday, Sept. 20, at the Hutchinson High School auditorium.While men have traditionally dominated the field of brass performance, that isn’t true any longer.Seraph Brass is an example of that.
Orlando City signs coach Adrian Heath to extension through 2017
Adrian Heath stuck with Orlando City through six seasons in U.S. soccer’s lower tiers–including two when the organization was based in Austin, Texas–and rejected multiple offers to coach in MLS with other clubs. Now, Orlando City is sticking with Heath. On Friday, the MLS expansion franchise will announce a contract extension that will cover Heath through the 2017 season. His current deal was set to expire next winter.
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