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Markus A. Martinez Holst on Muck Rack

Markus A. Martinez Holst

As seen in: Nature
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Response to comment on: cardiovascular and prostate cancer risk associated with testosterone replacement therapy—a systematic review and meta-analysis of 41 randomized controlled trials

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By Carlos A. Garcia-Becerra, Maria I. Arias-Gallardo, Jesus E. Juarez-Garcia, Federico Eskenazi, Juan Dugarte, Veronica Soltero-Molinar, Natalia Garcia-Becerra, Carlos García-Gutiérrez, Markus A. Martinez Holst
| Nature Verified
We sincerely thank Dr. Sharifan for his thoughtful comment [1] regarding our recently published systematic review and meta-analysis evaluating the cardiovascular and prostate safety of testosterone replacement therapy (TRT) [2]. We appreciate the opportunity to further discuss the interpretation of safety evidence, particularly the limitations of relying solely on p values to infer safety and the opportunity to address the important methodological concerns raised in the comment.
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