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Markus Kirolos Youssef on Muck Rack

Markus Kirolos Youssef

As seen in: Nature, BioRxiv
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Articles

Androgen receptor is a determinant of melanoma targeted drug resistance - Nature Communications

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By Anastasia Samarkina, Markus Kirolos Youssef, Paola Ostano, Giovanna Chiorino, Sandro Goruppi, Tatiana Proust
| Nature Verified
Abstract Melanoma provides a primary benchmark for targeted drug therapy. Most melanomas with BRAFV600 mutations regress in response to BRAF/MEK inhibitors (BRAFi/MEKi). However, nearly all relapse within the first two years, and there is a connection between BRAFi/MEKi-resistance and poor response to immune checkpoint therapy. We reported that androgen receptor (AR) activity is required for melanoma cell proliferation and tumorigenesis.
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DNA methylation sites in early adulthood characterised by pubertal timing and development: A twin study

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By Aino Heikkinen, Emir Sehovic, Stephanie Marie Zellers, Markus Kirolos Youssef
| BioRxiv
Thank you for your interest in spreading the word about bioRxiv. NOTE: Your email address is requested solely to identify you as the sender of this article. Your Email * Your Name * Send To * Enter multiple addresses on separate lines or separate them with commas. Message Subject (Your Name) has forwarded a page to you from bioRxiv Message Body (Your Name) thought you would like to see this page from the bioRxiv website.
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