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Marsus Pumar

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Oligoclonal expansion of atypical Vδ2 − γδ T cells in Good’s Syndrome

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By Esther Bandala-Sanchez, Josh Chatelier, Kerry Ramsay, Alison Morey, Sylvia Tsang, Julian Bosco, Silvia Sánchez-Ramón, Kissy Guevara-Hoyer, Jesús Fuentes-Antrás, Jack Godsell, Kymble Spriggs, Anouk von Borstel, Samantha Chan, Lauren J. Howson, Laura Scolamiero, Maureen Forde, Marsus Pumar
| Nature Verified
Abstract Good’s syndrome is a rare adult-onset immunodeficiency characterized by thymoma, hypogammaglobulinemia, B-cell lymphopenia, and T-cell dysfunction. Despite well-characterized defects in conventional immune subsets, the impact of this disorder on unconventional T cells, including γδ T cells, remains largely unexplored.
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