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Marta Columbaro on Muck Rack

Marta Columbaro

As seen in: MDPI, Future Medicine
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Articles

Altered Mitochondrial Dynamic in Lymphoblasts and Fibroblasts Mutated for FANCA-A Gene: The Central Role of DRP1

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By Nadia Bertola, Silvia Bruno, Marta Columbaro, Cristina Capanni
| MDPI
Abstract : Fanconi anemia (FA) is a rare genetic disorder characterized by bone marrow failure and aplastic anemia. So far, 23 genes are involved in this pathology, and their mutations lead to a defect in DNA repair. In recent years, it has been observed that FA cells also display mitochondrial metabolism defects, causing an accumulation of intracellular lipids and oxidative damage. However, the molecular mechanisms involved in the metabolic alterations have not yet been elucidated.
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Rapid and efficient magnetization of mesenchymal stem cells by dendrimer-functionalized magnetic nanoparticles

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By Nunzia Di Maggio, Elisa Martella, Steve Meikle, Marta Columbaro, Enrico Lucarelli
| Future Medicine Verified
Rapid and efficient magnetization of mesenchymal stem cells by dendrimer-functionalized magnetic nanoparticles Aim: Rapid and efficient magnetization of human bone marrow stromal cells (BMSC) through functionalized magnetic nanoparticles (MNP). Methods: MNP were functionalized with poly(epsilon-lysine) dendrons exposing carboxybetaine residue (CB-MNP) to enhance binding to the cellular glycocalix. BMSC were incubated with CB-MNP or non-functionalized PAA-MNP for 5–30 min in suspension.
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